Published January 2019 | Version v1
Journal article

Myocardial Perfusion Imaging for the Evaluation of Ischemic Heart Disease in Women

  • 1. Diagnóstico Maipú, Departments of Nuclear Medicine and Cardiovascular Imaging (Argentina)
  • 2. Universidad de Buenos Aires, Instituto de Fisiología, Biología Molecular y Neurociencias, Consejo Nacional de Investigaciones Científicas y Técnicas, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular (Argentina)

Description

Purpose of the Review

To review the value of myocardial blood flow and coronary flow reserve (CFR) measurements, as assessed by positron emission tomography (PET), in women with suspected ischemic heart disease.

Recent Findings

CFR is a noninvasive measure of coronary vasomotor function that integrates the hemodynamic effects of epicardial coronary stenosis, diffuse atherosclerosis, and microvascular dysfunction on myocardial tissue perfusion and has emerged as an imaging marker of cardiovascular risk, independently of the degree of obstructive coronary artery disease (CAD).

Summary

Normal coronary arteries or nonobstructive CAD is a common finding in women with ischemia. Thus, assessment of risk based on a coronary stenosis approach may fail in women. PET is able to quantify absolute myocardial blood flow and CFR which may help to elucidate other mechanisms involved such as microvascular dysfunction and diffuse epicardial CAD, responsible for the disease in women.

Additional details

Publishing Information

Journal Title
Current Cardiovascular Imaging Reports (Print)
Journal Volume
12
Journal Issue
1
Journal Page Range
p. 1-7
ISSN
1941-9066

Optional Information

Copyright
Copyright (c) 2019 Springer Science+Business Media, LLC, part of Springer Nature
Notes
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