Ampicillin radioprotector effect

This paper deals with the effect of ampicillin during irradiation and recovery of the Bacillus licheniformis RI 75-1 stump with a savage genotype of recovery exposed to ionizing radiations and treated with gamma quantums. Previous research enabled to prove that in Bacillus licheniformis spores suspensions, irradiated of vegetative cells in ampicillin at D-1--0- dose, causes significative lethal increases. In this paper, The irradiation of vegetative cells in presence of 5 mcg/ml of ampicillin increases the viability at doses above 1 kGy. the survival rates was raised when vegetative cells of Bacillus lincheniformis were irradiated at 1.2 kGy and recovered in a nutrient environment during 2 hours (LHR) in presence of ampicillin. Twenty-two stumps of Bacillus licheniformis obtained through different mutagenic treatments were studied in relation to the resistance of ampicillim and at 3 Kgy gamma quantums and a direct correlation between these two was stablished. Previous treatment with ampicillin of the vegetative cells from the Bacillus licheniformis increased the number of resistants to gamma quantums. There was no information about this phenomenom in literature consulted