Published 1985
| Version v1
Journal article
Circular chromatin complexes in human lymphocytes high-resolution autoradiography
- 1. Instituto Butantan, Sao Paulo, SP (Brazil). Servico de Genetica
Description
Transcriptionally active chromatin fibers were observed in chromosomes presenting the loops/scaffold configuration. The active fibers showed altered nucleosomes and presented multiforked aspects which led to the formation of ring complexes. The ribonucleoprotein transcripts (RNP) appeared as networks of 0.1 μm or multiples tandemly disposed along the fiber. It is suggested that the ring complexes belong to the human genome. The possibility that these circular structures come from a prokaryote is also considered. (author)
Abstract (Portuguese)
Fibras de cromatina ativas em transcricao foram observadas em cromossomos humanos. Esses cromossomos mostram configuracoes do tipo ''loops/scaffold''. As fibras ativas tem nucleossomos alterados e apresentam aspectos ''multi-forked'' os quais levam a formacao de aneis. Os transcritos de Ribonucleoproteina (RNP) aparecem como emaranhados de 0,1 μm ou multiplos dispostos em serie ao longo de fibra. Sugere-se que os complexes circulares de cromatina pertencem ao genoma humano. A possibilidade de que os aneis provem de procariotos e tambem discutida. (autor)Additional details
Publishing Information
- Journal Title
- Revista Brasileira de Genetica
- Journal Volume
- 8
- Journal Issue
- 2
- Series
- Rev. Bras. Genet.
- Journal Page Range
- 385-394
- ISSN
- 0100-8455
- CODEN
- RBGED
INIS
- Country of Publication
- Brazil
- Country of Input or Organization
- Brazil
- INIS RN
- 21067864
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES;
- Descriptors DEI
- AUTORADIOGRAPHY; CHROMATIN; LYMPHOCYTES; NUCLEOSOMES
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; LEUKOCYTES; MATERIALS; SOMATIC CELLS