Clinical significance of measurement of changes of plasma leptin and serum NPY levels after hemodialysis in patients with chronic renal failure
Description
Objective: To explore the clinical significance of changes of plasma leptin and serum NPY levels after hemodialysis in patients with chronic renal failure. Methods: Plasma leptin and serum NPY levels were measured with RIA both before and after hemodialysis in 31 patients with chronic renal failure as well as in 35 controls. Results: Before hemodialysis,plasma leptin and serum NPY levels were significantly higher in the patients than those in controls (P<0.01). After hemodialysis for 1 week the levels, though dropped markedly, still remained significantly higher than those in controls (P<0.05). Conclusion: The levels of leptin and NPY were significantly increased in patients with chronic renal failare. Hemodialysis could increase, the clearance rate of leptin and NPY and partially correct the levels with important clinical value. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 23
- Journal Issue
- 2
- Journal Page Range
- p. 136-137
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 44076102
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BIOLOGICAL FUNCTIONS; BLOOD; BLOOD PLASMA; DIAGNOSIS; FAILURES; KIDNEYS; LEPTIN; PATIENTS; PEPTIDES; RADIOIMMUNOASSAY; SURGERY; THERAPY
- Descriptors DEC
- BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BODY; BODY FLUIDS; DIAGNOSTIC TECHNIQUES; HORMONES; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; MEDICINE; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; PEPTIDES; POLYPEPTIDES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; TRACER TECHNIQUES
Optional Information
- Notes
- 1 tabs., 7 refs.