Published October 23, 1974 | Version v1
Report Restricted

Parabiosis, radiation and carcinogenesis in the rat

Creators

Description

Parabiosis extended the survival time of rats exposed to 1000 R of x radiation when the partner was shielded and enabled the appraisal of radiation carcinogenesis following application of a radiation dose normally in the lethal range. The incidence of leukemia, breast cancer in females, and osteogenic sarcoma in irradiated pariabionts was compared with that of their shielded partners. Results showed that irradiated partners not only developed more tumors by 300 to 900 days post-irradiation but developed tumors about two months earlier than either their partners or other control animals and many irradiated animals developed multiple tumors. (U.S.)

Availability note (English)

MF available from INIS under the Report Number.

Files

Restricted

The record is publicly accessible, but files are restricted to users with access.

Additional details

Publishing Information

Imprint Pagination
9 p.
Report number
COO--3017-18

Conference

Title
11. international cancer congress.
Dates
20 Oct 1974.
Place
Florence, Italy.

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
6209630
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ACUTE IRRADIATION; BIOLOGICAL RADIATION EFFECTS; CARCINOGENESIS; DELAYED RADIATION EFFECTS; LETHAL IRRADIATION; NEOPLASMS; PARABIOSIS; RADIATION EFFECTS; RATS; RESPONSE MODIFYING FACTORS
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; DISEASES; IRRADIATION; MAMMALS; MOSAICISM; PATHOGENESIS; RODENTS; VERTEBRATES

Optional Information

Secondary number(s)
CONF-741034--5.