Finite Element Approach Using Electrical Tomography for Bioassay Application

Single-cell imaging is a part bioassay application that is highly used in the studies of microbiology. This bioassay application is used in order to determine the cell activity, behaviour and reaction as well as electrical properties and characteristic. Most of this can be achieved by using mass spectrometry, impedance analyser and flow cytometry. Currently, there is an emerging trend of on-chip integrated device that allows bioassay application to be performed real time. However, in terms of cell monitoring, which allows us to view the cross section image of cell, there is much to be explored. As each cell is composed of different material with specific relative permittivity, Electrical Capacitance Tomography is chosen to determine the electrical properties and spatial distribution of cell. Therefore, the purpose of this research is to simulate Electrical Capacitance Tomography for yeast cell growth in order to determine the most suitable configuration needed for ECT system. (paper)