Role of 18-fluorodeoxyglucose positron emission tomography metabolic radiomics in predicting treatment response in patients with nonsmall cell lung cancer

Lung cancer accounts for 5.9% cancer cases and 8.1% cancer-related deaths in India. At the time of presentation, most patients have locally advanced or metastatic disease. Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) plays a crucial role in staging and evaluating treatment response in such patients. It characterizes tumor heterogeneity in the form of PET image-derived quantitative indices. These indices could be used in predicting therapy response which will help in guiding treatment decisions. Textural analysis parameters could provide prognostic information and guide treatment decisions in NSCLC patients and possibly in other malignancies as well. Larger multi centric studies are needed for better insight