Published April 1995 | Version v1
Journal article Metadata-only

A study on 186Re labelling of bleomycin

Creators

  • 1. The Inst. of Nuclear Physics and Chemistry, CAEP, Chengdu (China)

Description

The influence of several factors on 186Re-BLM formation is investigated by means of Sn(II) reducing method. The results show that the labelling yield is mainly dependent on the pH value in reaction medium, and that sodium gluconate is a suitable protecting agent to avoid Re-oxidation of the reduced Re. The method for preparing 186Re-BLM is described with labelling yield up to 98% in the pH range from 3 to 4.5

Additional details

Publishing Information

Journal Title
Nuclear Techniques
Journal Volume
18
Journal Issue
4
Journal Page Range
p. 231-234.
ISSN
0253-3219
CODEN
NUTEDL

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
26065513
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
BLEOMYCIN; CHEMICAL REACTION YIELD; GLUCONIC ACID; LABELLING; NEOPLASMS; PH VALUE; RADIOPHARMACEUTICALS; RADIOTHERAPY; REDUCTION; RHENIUM 186; SODIUM COMPOUNDS; TIN COMPOUNDS
Descriptors DEC
ALKALI METAL COMPOUNDS; ANTI-INFECTIVE AGENTS; ANTIBIOTICS; ANTIMITOTIC DRUGS; ANTINEOPLASTIC DRUGS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; DAYS LIVING RADIOISOTOPES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; HEAVY NUCLEI; HYDROXY ACIDS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RHENIUM ISOTOPES; THERAPY; YEARS LIVING RADIOISOTOPES; YIELDS