Published April 1992
| Version v1
Journal article
Radiation dose as a factor in host preparation for bone marrow transplantation across different genetic barriers
Description
Engraftment of donor bone marrow in relation to total body irradiation (TBI) dose was studied in syngeneic (B6→B6), MHC-compatible (BALB.B→B6) and MHC-incompatible allogeneic (BALB/c→B6) murine bone marrow transplantation (BMT) models. The steep dose-response relationships show how engraftment is critically dependent on TBI dose, as well as the genetic disparity between donor and host. (author)
Additional details
Publishing Information
- Journal Title
- International Journal of Radiation Biology
- Journal Volume
- 61
- Journal Issue
- 4
- Series
- Int. J. Radiat. Biol.
- Journal Page Range
- 501-510
- ISSN
- 0955-3002
- CODEN
- IJRBE
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 23057927
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BONE MARROW; DOSE-RESPONSE RELATIONSHIPS; GRAFT-HOST REACTION; RESPONSE MODIFYING FACTORS; TRANSPLANTS; WHOLE-BODY IRRADIATION
- Descriptors DEC
- BODY; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; IRRADIATION; ORGANS; TISSUES