Published 1988
| Version v1
Book
Immunological probes for lesions and repoair patches in DNA
Description
This paper describes two immunological approaches for the detection of DNA damage and its repair. The first uses a monoclonal antibody to directly measure the production and removal of one type of oxidized base, thymine glycol; the second uses an antibody to detect the repair synthesis event itself and, when combined with the use of molecular biological techniques, can be used to monitor the production and removal of lesions in specific sequences within the genome
Additional details
Publishing Information
- Publisher
- Marcel Dekker Inc.
- Imprint Place
- New York, NY (USA)
- Imprint Title
- DNA repair
- Imprint Pagination
- 532 p.
- Series
- A laboratory manual of research procedures.
- Journal Page Range
- p. 311-326.
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21086708
- Subject category
- S60: APPLIED LIFE SCIENCES; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- AFLATOXINS; BENZOPYRENE; BIOLOGICAL PATHWAYS; BIOLOGICAL RADIATION EFFECTS; CARCINOGENESIS; DNA; DNA REPAIR; DNA SEQUENCING; ENDONUCLEASES; IONIZING RADIATIONS; LABELLING; MOLECULAR BIOLOGY; MONOCLONAL ANTIBODIES; NITROSOUREAS; PYRIMIDINE DIMERS; RADIATION EFFECTS; RADIOIMMUNOASSAY; STRAND BREAKS; ULTRAVIOLET RADIATION
- Descriptors DEC
- ANTIBODIES; ANTIGENS; AROMATICS; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; CONDENSED AROMATICS; DIMERS; ELECTROMAGNETIC RADIATION; ENZYMES; ESTERASES; HYDROCARBONS; HYDROLASES; IMMUNOASSAY; ISOTOPE APPLICATIONS; NITROSO COMPOUNDS; NUCLEASES; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PATHOGENESIS; PHOSPHODIESTERASES; RADIATIONS; STRUCTURAL CHEMICAL ANALYSIS; TOXINS; TRACER TECHNIQUES