Published June 1986 | Version v1
Journal article Metadata-only

Protection of mouse chromosomes against whole-body gamma irradiation by SH-compounds

Creators

  • 1. Rajasthan Univ., Jaipur (India). Radiation Biology Lab.

Description

Experiments were performed to study the protective effect of Wr-2721 (S-2-(3-aminopropylamino)phosphorothioic acid), a derivative of cysteamine and MPG (2-mercaptopropionylglycine) individually on the bone-marrow chromosomes of adult mice when administered before acute whole-body exposures. Taking percentage aberrant cells for 0.5 Gy as the base, the dose reduction factor for MPG was calculated to be 2.6 and that for WR-2721 to be 4.5. (U.K.)

Additional details

Publishing Information

Journal Title
Br. J. Radiol.
Journal Volume
59
Journal Issue
702
Series
Br. J. Radiol.
Journal Page Range
625-627
ISSN
0007-1285
CODEN
BJRAA

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
17068063
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
CHROMOSOMAL ABERRATIONS; COMPARATIVE EVALUATIONS; GAMMA RADIATION; MEA; MICE; RADIOSENSITIVITY; THIOLS; WHOLE-BODY IRRADIATION
Descriptors DEC
AMINES; ANIMALS; DRUGS; ELECTROMAGNETIC RADIATION; EVALUATION; EXTERNAL IRRADIATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MUTATIONS; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; RADIATIONS; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; RODENTS; VERTEBRATES