Published January 1989 | Version v1
Journal article Metadata-only

Synthesis of NCL-6-Et82Br and its distribution in mouse's organs

Creators

  • 1. Beijing Normal Univ. (China). Inst. of Applied Chemistry
  • 2. Kyushu Univ., Japan

Description

Bromine-82 labelled 6β-(2'-bormo) ethyl-19-norcholest-5 (10)-en-3β-ol (i.e. NCL-6-Et82Br) has been prepared both by the crown ether method and by the hydrothermal melting method. A study on its distribution in mouse's organs showed a rather selectiver localization of radioactivity in adrenal gland, in which the absorption of NCL-6-Et82Br was found to be higher than that of CL-6-82Br or NCL-6-82Br. The adrenal/liver and adrenal/kidney ratios of the titled compound were shown to be higher than those of CL-6-82Br, and near those of NCL-6-82Br

Additional details

Publishing Information

Journal Title
Nuclear Techniques
Journal Volume
12
Journal Issue
1
Series
Nucl. Tech.
Journal Page Range
54-57
ISSN
0253-3219
CODEN
NUTED

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
21042423
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ADRENAL GLANDS; BROMINE COMPOUNDS; BROMINE 82; CHOLESTEROL; CONTRAST MEDIA; LABELLED COMPOUNDS; LABELLING; MICE; TISSUE DISTRIBUTION
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; BROMINE ISOTOPES; DAYS LIVING RADIOISOTOPES; DISTRIBUTION; ENDOCRINE GLANDS; GLANDS; HALOGEN COMPOUNDS; HYDROXY COMPOUNDS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPES; RODENTS; STEROIDS; STEROLS; VERTEBRATES