Published May 2004
| Version v1
Journal article
Long-term retention of dextran-coated magnetite nanoparticles in the liver and spleen
Description
A dextran-coated, magnetite-based magnetic fluid sample (DexMF) was tested through morphological analysis of mice organs. Clusters of magnetic nanoparticles (MNPs) were observed in liver and spleen tissues from 1 h up to 6 months after DexMF administration. In spite of long-term retention of MNPs, no morphological alterations, including damaged cells, were observed in the analyzed organs. The data suggest that DexMF sample is biocompatible and adequate for further biomedical tests
Additional details
Identifiers
- DOI
- 10.1016/j.jmmm.2003.12.852;
- PII
- S030488530301850X;
Publishing Information
- Journal Title
- Journal of Magnetism and Magnetic Materials
- Journal Volume
- 272-276
- Journal Issue
- 6
- Journal Page Range
- p. 2434-2435
- ISSN
- 0304-8853
- CODEN
- JMMMDC
Conference
- Title
- International conference on magnetism
- Acronym
- ICM 2003
- Dates
- 27 Jul - 1 Aug 2003
- Place
- Rome (Italy)
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 36029885
- Subject category
- S60: APPLIED LIFE SCIENCES; S36: MATERIALS SCIENCE;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- DEXTRAN; FLUIDS; LIVER; MAGNETITE; MICE; MORPHOLOGY; NANOSTRUCTURES; PARTICLES; RETENTION; SPLEEN
- Descriptors DEC
- ANIMALS; BLOOD SUBSTITUTES; BODY; CARBOHYDRATES; DIGESTIVE SYSTEM; DRUGS; GLANDS; HEMATOLOGIC AGENTS; IRON ORES; MAMMALS; MINERALS; ORES; ORGANIC COMPOUNDS; ORGANS; OXIDE MINERALS; POLYSACCHARIDES; RODENTS; SACCHARIDES; VERTEBRATES
Optional Information
- Copyright
- Copyright (c) 2004 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.