Published November 15, 2008
| Version v1
Journal article
In vitro biological performance of nano-particles on the surface of hydroxyapatite coatings
Creators
- 1. School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083 (China)
- 2. National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050 (China)
- 3. School of Materials Science and Engineering, Shandong University, Jinan 250061, Shandong (China)
Description
The biocompatibility of a kind of heat-treated bilayer hydroxyapatite (HA) coatings with nano-particles was investigated, mainly in terms of the immersion in simulated body fluid (SBF) and osteoblast adhesion. Scanning electron microscopy (SEM) was used to observe the morphology of coatings and cellular adhesion. The phases present in the coatings were determined by X-ray diffraction (XRD). Calcium ion (Ca2+) concentration in SBF was measured by Atomic absorption spectrophotometer. The results show nano-HA heat-treated at 650 deg. C for 0.5 h (BBCs) is comparatively stable during immersion in SBF and favor of the adhesion of osteoblasts. Cellular filopodia adhere firmly to the nano-particles and stretch in various direction
Availability note (English)
Available from http://dx.doi.org/10.1016/j.apsusc.2008.06.110Additional details
Identifiers
- DOI
- 10.1016/j.apsusc.2008.06.110;
- PII
- S0169-4332(08)01539-0;
Publishing Information
- Journal Title
- Applied Surface Science
- Journal Volume
- 255
- Journal Issue
- 2
- Journal Page Range
- p. 375-378
- ISSN
- 0169-4332
- CODEN
- ASUSEE
Conference
- Title
- 1. international symposium on surfaces and interfaces of biomaterials
- Acronym
- SIB '07
- Dates
- 5-7 Oct 2007
- Place
- Chengdu (China)
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 40084320
- Subject category
- S36: MATERIALS SCIENCE;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ABSORPTION; ABSORPTION SPECTRA; APATITES; BODY FLUIDS; CALCIUM IONS; COATINGS; CONNECTIVE TISSUE CELLS; HEAT TREATMENTS; PARTICLES; PERFORMANCE; SCANNING ELECTRON MICROSCOPY; SIMULATION; SPECTROPHOTOMETERS; SURFACES; TEMPERATURE RANGE 0400-1000 K; X-RAY DIFFRACTION
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL MATERIALS; CHARGED PARTICLES; COHERENT SCATTERING; DIFFRACTION; ELECTRON MICROSCOPY; IONS; MATERIALS; MEASURING INSTRUMENTS; MICROSCOPY; MINERALS; PHOSPHATE MINERALS; SCATTERING; SOMATIC CELLS; SORPTION; SPECTRA; TEMPERATURE RANGE
Optional Information
- Copyright
- Copyright (c) 2008 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.