Published 1984 | Version v1
Report Open

The role of genotype in protection against gamma-radiation of E. coli cells by glycerol

Creators

Description

The protective effect of glycerol and anoxia on the survival of γ-irradiated E.coli cells of wild type, recA-, polA- mutants has been investigated. The protection by glycerol increases from recA- mutant to wild type and polA- mutant with dose modifying factors (DMF) being 2.03+-0.12, 2.52+-0.25, and 2.80+-0.26. Analogically the protection by hypoxia is genetically determined, too. The value of oxygen effect increases from 1.77+-0.23 for recA- mutant to 3.38+-0.29 for wild type cells and 4.66+-0.41 for polA--mutant. The oxygen independent component of glycerol protection is geltically independent (DMF=2). Possible mechanisms of genetic determination of the protection by glycerol and anoxia are discussed

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MF available from INIS under the Report Number.

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Additional details

Additional titles

Original title (Russian)
Рол' генотипа в радиозащитном действии глицерина при γ-облучении бактерий Есчеричиа cоли

Publishing Information

Imprint Pagination
12 p.
Report number
JINR--19-84-798

INIS

Country of Publication
USSR
Country of Input or Organization
USSR
INIS RN
16057633
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ANOXIA; CESIUM 137; CULTURE MEDIA; DNA; DOSE-RESPONSE RELATIONSHIPS; ESCHERICHIA COLI; GAMMA RADIATION; GENOTYPE; GLYCEROL; MUTANTS; RADIATION PROTECTION; RADIOSENSITIVITY; RESPONSE MODIFYING FACTORS; STRAND BREAKS; SURVIVAL CURVES
Descriptors DEC
ALCOHOLS; BACTERIA; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CESIUM ISOTOPES; ELECTROMAGNETIC RADIATION; HYDROXY COMPOUNDS; INTERMEDIATE MASS NUCLEI; IONIZING RADIATIONS; ISOTOPES; MICROORGANISMS; NUCLEI; NUCLEIC ACIDS; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; RADIATIONS; RADIOISOTOPES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
19 refs.; 4 figs.; 3 tabs.; submitted to the journal Studia Biophys.