Published December 1980
| Version v1
Journal article
Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular, and intracellular events in matrix proteolysis by macrophages in culture
Description
The aim of the present study was to determine the localization of macrophage-mediated degradation of matrix proteins. The sites of matrix degradation were examined ultrastructurally, and the effects of modulation of macrophage secretion, endocytosis, and activity of macrophage hydrolases on matrix degradation were monitored biochemically
Additional details
Publishing Information
- Journal Title
- J. Exp. Med.
- Journal Volume
- 152
- Series
- J. Exp. Med.
- Journal Page Range
- 1537-1553
- ISSN
- 0022-1007
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 14749926
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BIOCHEMISTRY; BIOLOGICAL EFFECTS; BIOLOGICAL LOCALIZATION; CELL CULTURES; COLCHICINE; CONNECTIVE TISSUE; DECOMPOSITION; DEXAMETHASONE; ENZYME INHIBITORS; LYSOSOMES; MACROPHAGES; MICE; MORPHOLOGICAL CHANGES; PHAGOCYTOSIS; PROLINE; PROSTAGLANDINS; PROTEOLYSIS; SCANNING ELECTRON MICROSCOPY; STIMULATION; TRANSMISSION ELECTRON MICROSCO; TRITIUM COMPOUNDS; ULTRASTRUCTURAL CHANGES
- Descriptors DEC
- ADRENAL HORMONES; ALKALOIDS; AMINES; AMINO ACIDS; ANIMAL CELLS; ANIMALS; ANTIMITOTIC DRUGS; AZOLES; BODY; CARBOXYLIC ACIDS; CELL CONSTITUENTS; CHEMICAL REACTIONS; CHEMISTRY; CONNECTIVE TISSUE CELLS; CORTICOSTEROIDS; DRUGS; ELECTRON MICROSCOPY; GLUCOCORTICOIDS; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; HORMONES; HYDROGEN COMPOUNDS; HYDROXY COMPOUNDS; KETONES; MAMMALS; MICROSCOPY; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANOIDS; PHAGOCYTES; PREGNANES; PYRROLES; PYRROLIDINES; RODENTS; SOMATIC CELLS; STEROID HORMONES; STEROIDS; TISSUES; VERTEBRATES