Published July 1994 | Version v1
Journal article Metadata-only

The influence of kagocel on post-irradiation recovery of hematopoiesis ans immunity of mice after exposure to sublethal dose of ionizing radiation

Creators

Description

The efficiency of interferon inductor, kagocel, in hemopoiesis and immunity disturbances caused by sublethal doses of ionizing radiation was investigated. The experiments showed that irradiation of mice with a dose of 0.9 Gy causes short-term frop of a number of cells in the bone marrow and lymphoid organs, reducing of CFUs and CFU-GM levels, decrease in a number of antibody-formation cells in spleen and falling of reaction of blast-irradiation recovery of bone marrow hemotopoiesis, stimulated compensatory potential of hematopoietic system and increase in antiviral resistance of irradiated animals

Additional details

Additional titles

Original title (Russian)
Влияние кагоцела на пострадиационное восстановление кроветворения и иммунного статуса у мышей при действии ионизирующей радиации в сублетальной дозе

Publishing Information

Journal Title
Radiatsionnaya Biologiya, Radioehkologiya
Journal Volume
34
Journal Issue
4-5
Journal Page Range
p. 572-577.
ISSN
0869-8031
CODEN
RBIREJ

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
26024364
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ANTIBODY FORMATION; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL RECOVERY; BLOOD FORMATION; BONE MARROW; GAMMA RADIATION; IMMUNITY; INTERFERON; LETHAL RADIATION DOSE; LYMPHOCYTES; MICE; RADIOPHARMACEUTICALS; RESPONSE MODIFYING FACTORS; SPLEEN; STIMULATION; TIME DEPENDENCE; VIRUSES
Descriptors DEC
ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DRUGS; ELECTROMAGNETIC RADIATION; HEMATOPOIETIC SYSTEM; IONIZING RADIATIONS; LABELLED COMPOUNDS; LETHAL DOSES; LEUKOCYTES; MAMMALS; MATERIALS; MICROORGANISMS; ORGANS; PARASITES; RADIATION DOSES; RADIATION EFFECTS; RADIATIONS; RADIOACTIVE MATERIALS; RODENTS; SOMATIC CELLS; TISSUES; VERTEBRATES