A case of malignant fibrous histiocytoma following radiation therapy for superior sulcus tumor

We recently observed a case of presumed radiation-induced malignant fibrous histiocytoma (MFH), which developed 20 years after radiation therapy (74 Gy) for superior sulcus tumor. The radiation-induced brachial plexopathy occurred 10 years after completion of radiation therapy. The evolution of multimodality management for superior sulcus tumor increases the number of long-term surviving cases, the incidence of irradiation-induced secondary malignant tumor will increase. It is therefore necessary to survey these cases over a long period of time after radiation therapy. (author)