Analyzing the parameters affecting the estimation of glomerular filtration rate using ⁹⁹mTc- DTPA through gates method

To compare the variation in the (GFR) obtained using various methods of kidney depth estimation and positions of the background ROIs in a conventional gamma camera. Data was retrospectively analyzed from 17 patient subjected to GFR estimation with ^99mTc-DTPA (Diethylene Triamine Penta Acetic acid) using Gates method in a gamma camera (Symbia T16, Siemens Healthineers, USA) and 3 sample plasma sampling kidney depth estimation using Emory, Standard and Itoh methods with a standard intrarenal background ROI. Effect of perirenal background ROIs on the split renal function was also analyzed. The GFR obtained by plasma sampling was considered as reference standard. Emory and Itoh methods both show comparable GFR values to multiple plasma sampling. Choice of background ROI does not significantly affect the split renal function