Published May 1980 | Version v1
Journal article Metadata-only

Free-radical production in DNA after exposure to long wave ultraviolet radiation in the presence of photo-oxidized l-tryptophan

Creators

  • 1. Nauchno-Issledovatel'skij Tsentr 2-go Meditsinskogo Inst., Moscow (USSR)
  • 2. AN SSSR, Moscow. Inst. Khimicheskoj Fiziki
  • 3. Vsesoyuznyj Zaochnyj Politekhnicheskij Inst., Moscow (USSR)

Description

Ecological irradiation (lambda>300 nm) on the DNA in the presence of supposed endogenous sensitizers - the products of l-tryptophan and kinurenin oxidation has been studied. Revealed were formation of neutral thymin radicals at 77 K and their transformation into radicals of hydroxyde type in the presence of oxygen at 183 K. The action of long wave ultraviolet radiation in the prosence of sensitizers was analogous to that of the short wave ultraviolet radiation on the DNA, excluding the fact that in the latter case the ion-radicals of the DNA bases formed along with the neutral thymin radicals

Additional details

Additional titles

Original title (Russian)
Образование свободных радикалов в ДНК при облучении длинноволновым УФ-светом в присутствии фотоокисленного L-триптофана

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
20
Journal Issue
3
Series
Radiobiologiya.
Journal Page Range
343-348
ISSN
0033-8192

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
12638063
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Numerical Data
Descriptors DEI
DNA; ELECTRON SPIN RESONANCE; EXPERIMENTAL DATA; KYNURENINE; NEAR ULTRAVIOLET RADIATION; RADICALS; SPECTRA; THYMINE; TRYPTOPHAN
Descriptors DEC
AMINO ACIDS; AZINES; AZOLES; CARBOXYLIC ACIDS; DATA; ELECTROMAGNETIC RADIATION; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; INDOLES; INFORMATION; KETO ACIDS; MAGNETIC RESONANCE; NUCLEIC ACIDS; NUMERICAL DATA; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PYRIMIDINES; PYRROLES; RADIATIONS; RESONANCE; ULTRAVIOLET RADIATION; URACILS

Optional Information

Notes
For English translation see the journal Radiobiology (Translation) (USA).