Published March 1, 2011
| Version v1
Journal article
Dynamic model of gene regulation for the lac operon
Creators
- 1. Intelligent Modelling Lab, School of Computing, Engineering and Information Sciences, Northumbria University, Newcastle upon Tyne NE2 1XE (United Kingdom)
Description
Gene regulatory network is a collection of DNA which interact with each other and with other matter in the cell. The lac operon is an example of a relatively simple genetic network and is one of the best-studied structures in the Escherichia coli bacteria. In this work we consider a deterministic model of the lac operon with a noise term, representing the stochastic nature of the regulation. The model is written in terms of a system of simultaneous first order differential equations with delays. We investigate an analytical and numerical solution and analyse the range of values for the parameters corresponding to a stable solution.
Availability note (English)
Available from http://dx.doi.org/10.1088/1742-6596/286/1/012007Additional details
Identifiers
Publishing Information
- Journal Title
- Journal of Physics. Conference Series (Online)
- Journal Volume
- 286
- Journal Issue
- 1
- Journal Page Range
- [5 p.]
- ISSN
- 1742-6596
Conference
- Title
- Condensed matter and materials physics conference
- Acronym
- CMMP10
- Dates
- 14-16 Dec 2010
- Place
- Warwick (United Kingdom)
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 43042830
- Subject category
- S71: CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ANALYTICAL SOLUTION; DIFFERENTIAL EQUATIONS; DNA; ESCHERICHIA COLI; GENE REGULATION; GENES; NOISE; NUMERICAL SOLUTION; REGULATIONS; STOCHASTIC PROCESSES
- Descriptors DEC
- BACTERIA; EQUATIONS; LAWS; MATHEMATICAL SOLUTIONS; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS