Published June 1974
| Version v1
Journal article
Radioprotective potency of thiazine and thiazole derivatives
- 1. National Inst. of Radiological Sciences, Chiba (Japan)
Description
2-Amino-4, 6, 6-trimethyl-1, 3-thiazine and 2-amino-4-methylthiazole demonstrated a radioprotective action in mice irradiated with 70O R of X-rays, but did not show any protective action on radiation-induced killing of cultured HeLa cells. Since no evidence of liberation of SH group through ring opening was observed, the protective action of the compound in mice might be due to its pharmacological action.
Additional details
Identifiers
- DOI
- 10.1269/jrr.15.116;
Publishing Information
- Journal Title
- Journal of Radiation Research
- Journal Volume
- 15
- Journal Issue
- 2
- Series
- J. Radiat. Res.
- Journal Page Range
- 116-118
- ISSN
- 0449-3060
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 5146171
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- No Abstract
- Descriptors DEI
- AZINES; BIOLOGICAL RADIATION EFFECTS; HELA CELLS; LETHAL IRRADIATION; MICE; RADIATION PROTECTION; RADIOPROTECTIVE SUBSTANCES; SURVIVAL CURVES; SURVIVAL TIME; THIAZOLES; X RADIATION
- Descriptors DEC
- ANIMALS; AZOLES; BIOLOGICAL EFFECTS; DRUGS; ELECTROMAGNETIC RADIATION; HETEROCYCLIC COMPOUNDS; IONIZING RADIATIONS; IRRADIATION; MAMMALS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC SULFUR COMPOUNDS; RADIATION EFFECTS; RADIATIONS; RESPONSE MODIFYING FACTORS; RODENTS; VERTEBRATES
Optional Information
- Notes
- Letter-to-the-editor.; Updated automatically by Metadata and Full-Text Enrichment Agent