Automation of cells of radiopharmaceuticals production
Description
The 67Ga is an important radiopharmaceutical used to identify inflammatory processes in chronic illnesses, diagnosis by image of tumors in soft tissues and the possibility to evaluate the result for therapeutic intervention. In the present work a module of 67Ga processing was developed with the objective to reduce the interventions in the hot cell, in order to avoid oxidation caused by metallic materials, and consuming in hoses of the peristaltic pumps, that release residues that blocked the valves used in the process. With materials such as: acrylic, PVC, PEEK e teflon and they are used vacuum as method (way) of fluid transferences instead of peristaltic pump in the majority of the procedures, with this improvements the system can make shorter the lengths of transference hoses, increasing the yield in the process with less interventions for maintenance and time exposure of the workers, guaranteeing the quality and reducing the time of the processing. using a mobile system for displacement of the processing module making in the cleanness and maintenance of the cell that works with radioactive material. Reducing the time of exposure dose of the workers in compliance with RDC-17 of ANVISA, which ruling the Good Manufacturing Practice Procedures. (author)
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44066034.pdf
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Additional details
Additional titles
- Original title (Portuguese)
- Automacao de celulas de producao de radiofarmacos
Publishing Information
- Imprint Pagination
- 104 p.
- Report number
- INIS-BR--12499
INIS
- Country of Publication
- Brazil
- Country of Input or Organization
- Brazil
- INIS RN
- 44066034
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Thesis
- Descriptors DEI
- DIAGNOSIS; GALLIUM 67; HOT CELLS; IMAGES; NEOPLASMS; OCCUPATIONAL EXPOSURE; OXIDATION; PERSONNEL; PVC; RADIATION DOSES; RADIOPHARMACEUTICALS; TEFLON
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; CHEMICAL REACTIONS; CHLORINATED ALIPHATIC HYDROCARBONS; DAYS LIVING RADIOISOTOPES; DISEASES; DOSES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EQUIPMENT; FLUORINATED ALIPHATIC HYDROCARBONS; GALLIUM ISOTOPES; HALOGENATED ALIPHATIC HYDROCARBONS; INTERMEDIATE MASS NUCLEI; ISOTOPES; LABELLED COMPOUNDS; LABORATORY EQUIPMENT; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC CHLORINE COMPOUNDS; ORGANIC COMPOUNDS; ORGANIC FLUORINE COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC POLYMERS; PETROCHEMICALS; PETROLEUM PRODUCTS; PLASTICS; POLYETHYLENES; POLYMERS; POLYOLEFINS; POLYTETRAFLUOROETHYLENE; POLYVINYLS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SYNTHETIC MATERIALS