Published August 1987
| Version v1
Journal article
The role of ultraviolet-irradiated plasma in the inhibition of DNA synthesis in lymphocytes
Description
The auotologous plasma, isolated upon UV-irradiation of the whole blood, has an inhibitory effect on mitogen-induced blastogenesis of human lymphocytes. Its addition to the culture medium results in a statistically significant suppression of DNA synthesis in lymphocytes in the presence of phytohemagglutinin and concanavalin A. No such effect was observed with the use of pokeweed mitogen. Our studies show that this phenomenon is associated with photoconversion of the plasma components
Additional details
Additional titles
- Original title (Russian)
- Подавление синтеза DNK в лимфоцитах плазмой, подвергнутой UF-облучению
Publishing Information
- Journal Title
- Byull. Ehksp. Biol. Med.
- Journal Volume
- 104
- Journal Issue
- 8
- Series
- Byull. Ehksp. Biol. Med.
- Journal Page Range
- 205-206
- ISSN
- 0365-9615
- CODEN
- BEBMA
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 19040324
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOSYNTHESIS; BLOOD PLASMA; CONCANAVALIN A; DNA; INHIBITION; LYMPHOCYTES; PHYTOHEMAGGLUTININ; ULTRAVIOLET RADIATION
- Descriptors DEC
- AGGLUTININS; ANIMAL CELLS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CARBOHYDRATES; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; HEMAGGLUTININS; LEUKOCYTES; MATERIALS; MITOGENS; MUCOPROTEINS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; POLYSACCHARIDES; PROTEINS; RADIATIONS; SACCHARIDES; SOMATIC CELLS; SYNTHESIS