Published September 1, 2009 | Version v1
Journal article Metadata-only

Full-field transmission x-ray microscopy for bio-imaging

Creators

  • 1. Stanford Synchrotron Radiation Laboratory, Menlo Park CA 94025 (United States)
  • 2. Institute of High Energy Physics, Beijing (China)
  • 3. NASA Ames Research Center, Moffett Field, CA 94035 (United States)
  • 4. Cornell University, Ithaca NY 14853 (United States)
  • 5. Institute for National Measurement Standards, Ottawa ON K1A0R6 (Canada)
  • 6. Xradia Inc., Concord CA 94520 (United States)

Description

A full-field hard-x-ray microscope at SSRL has successfully imaged samples of biological and environmental origin at 40 nm resolution. Phase contrast imaging of trabeculae from a female mouse tibia, loaded in vivo to study the effects of weight-bearing on bone structure, revealed a complex network of osteocytes and canaliculi. Imaging of cordgrass roots exposed to mercury revealed nanoparticles with strong absorption contrast. 3D tomography of yeast cells grown in selenium rich media showed internal structure.

Availability note (English)

Available from http://dx.doi.org/10.1088/1742-6596/186/1/012081

Additional details

Identifiers

DOI
10.1088/1742-6596/186/1/012081;

Publishing Information

Journal Title
Journal of Physics. Conference Series (Online)
Journal Volume
186
Journal Issue
1
Journal Page Range
[3 p.]
ISSN
1742-6596

Conference

Title
9. international conference on X-ray microscopy
Dates
21-25 Jul 2008
Place
Zurich (Switzerland)

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
42027499
Subject category
S46: INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ABSORPTION; BIOLOGICAL MATERIALS; BONE CELLS; ENVIRONMENTAL MATERIALS; FEMALES; HARD X RADIATION; IN VIVO; MERCURY; MICE; MICROSCOPES; MICROSCOPY; NANOSTRUCTURES; RESOLUTION; SELENIUM; TIBIA; TOMOGRAPHY; X-RAY DETECTION; YEASTS
Descriptors DEC
ANIMAL CELLS; ANIMALS; BODY; CONNECTIVE TISSUE CELLS; DETECTION; DIAGNOSTIC TECHNIQUES; ELECTROMAGNETIC RADIATION; ELEMENTS; EUMYCOTA; FUNGI; IONIZING RADIATIONS; MAMMALS; MATERIALS; METALS; MICROORGANISMS; ORGANS; PLANTS; RADIATION DETECTION; RADIATIONS; RODENTS; SEMIMETALS; SKELETON; SOMATIC CELLS; SORPTION; VERTEBRATES; X RADIATION