Comparison of FNAC and histopathological results for 4 cm or larger benign thyroid nodules

To assess the fine-needle aspiration cytology (FNAC) and histopathological results of thyroid nodules sized 4 cm or larger with benign cytology. Study Design: Analytical study. Place and Duration of Study: Health Science University Umraniye Training and Research Hospital, Istanbul, Turkey. Methodology: Patients with thyroid nodule size 4 cm. or larger and benign FNAC results were included in the study. All patients' age, gender, size of nodule, results of FNAC, types of surgery and histopathological results of thyroid specimen were extracted from patients' files. Results: Out of 720 patients, who underwent thyroidectomy between January 2009 and January 2018, 310 patients with a benign FNAC results, between the ages of 18 and 78 years, with nodule diameters ranging from 4 to 8.4 cm were included in the study. Of these 310 patients, 243 (78.4%) were females and 67 (21.6%) were males. In the final histopathological examination, thyroid carcinoma was detected in five of the cases (1.6%). Conclusion: The risk of malignancy in 4 cm and larger thyroid nodules with benign FNAC was as much as expected in other benign nodules. (author)