Published May 1992 | Version v1
Journal article

The effect of heart-and kidney-benefiting Chinese herbal medicines on the function of adrenergic receptors in brain tissues of analogue dementia rats

  • 1. Shanghai Coll. of TCM, Shanghai (China)

Description

Analogue dementia model of rats was produced by electrolytic lesion of brain. α-adrenergic receptors were assayed by radioligand binding assay (RRBA). It was found that Bmax of α1 receptors was decreased obviously in cerebral cortex, hippocampus and cerebellum of analogue dementia rats and was raised obviously by Heart-and Kidney-Benefiting Chinese Herbs as well as by Hydergin. The electrolytic lesion did not change the activity of MAO-B in model rat brains. Neither Heart-and Kidney-Benefiting Chinese Herb Medicines nor Hydergin showed marked effect on brain MAO-B activity of the model rats

Additional details

Publishing Information

Journal Title
Nuclear Techniques
Journal Volume
15
Journal Issue
5
Journal Page Range
p. 304-308.
ISSN
0253-3219
CODEN
NUTEDL