Selective retention of 147Pm in skeleton and its injury effect on immune cells of bone marrow studied by liquid scintillation counting
Creators
- 1. Suzhou Medical Coll., JS (China)
Description
The purpose of the present study is to ascertain the retention reculiarity in organism by varying doses of 147Pm and its injury effect on immune cells of bone marrow. The experimental groups of BALB/C strain mice were injected intravenously with 37, 1.85 x 102, 9.25 x 102, 3.7 x 103, 1.85 x 104 and 1.85 x 105 Bq/g respectively. The radioactivities in liver, kidney, skeleton, lung and blood samples were determined by liquid scintillation. The results showed that the most of 147Pm was deposited in skeleton, then in liver, blood, kidney and lung. The absorbed doses in skeleton increases as the intake of 147Pm increases. At the same time, the incorporation of 3H-TdR in immune cell of bone marrow is remarkably decreased. It shows, under the radiation of 147Pm, the DNA synthesis function is inhibited, and the immune cell of bone marrow is seriously injured
Availability note (English)
MF available from INIS under the Report Number.Files
22043251.pdf
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Additional details
Publishing Information
- Imprint Pagination
- 5 p.
- Report number
- CNIC--00317
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 22043251
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BONE MARROW CELLS; BONE TISSUES; FISSION PRODUCTS; KIDNEYS; LIVER; PROMETHIUM 147; RADIATION DOSES; RADIATION INJURIES; RETENTION; TISSUE DISTRIBUTION; TRACER TECHNIQUES
- Descriptors DEC
- ANIMAL CELLS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CONNECTIVE TISSUE; CONNECTIVE TISSUE CELLS; DIGESTIVE SYSTEM; DISEASES; DISTRIBUTION; GLANDS; INJURIES; INTERMEDIATE MASS NUCLEI; ISOTOPE APPLICATIONS; ISOTOPES; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; PROMETHIUM ISOTOPES; RADIATION EFFECTS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RARE EARTH NUCLEI; SOMATIC CELLS; TISSUES; YEARS LIVING RADIOISOTOPES
Optional Information
- Secondary number(s)
- SMC--0034.