Published November 1988
| Version v1
Journal article
DNA repair in mammalian nerve cells
Creators
Description
DNA synthesis in neurons of neocortex of newborn, 14- and 60-day-old rats after gamma-irradiation in vitro of isolated slices is investigated with the determination of labelled predecessor inclusion into nuclear DNA. 20 Gy dose gamma irradiation increases the DNA synthesis intensity in the neurons of all the animal age groups investigated. The induced DNA synthesis in neurons of newborn rats is higher than in the identical cells of 14- and 60-day-old animals. Peculiarities of DNA synthesis in the course of nerve cell differentiation are discussed
Additional details
Additional titles
- Subtitle (English)
- 2. DNA synthesis in neurons induced by gamma-irradiation of isolated rat neocortex slices
- Original title (Russian)
- Репарация DNK в нервных клетках млекопитающих
- Original subtitle (Russian)
- 2. Sintez DNK v nejtronakh, indutsirovannyj gamma-oblucheniem perezhivayushchikh srezov neokorteksa krys.
Publishing Information
- Journal Title
- Tsitologiya
- Journal Volume
- 30
- Journal Issue
- 11
- Series
- Tsitologiya.
- Journal Page Range
- 1338-1344
- ISSN
- 0041-3771
- CODEN
- TSITA
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 20044691
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- AGE DEPENDENCE; BIOLOGICAL RADIATION EFFECTS; BIOSYNTHESIS; CEREBRAL CORTEX; DNA; GAMMA RADIATION; IN VITRO; NERVE CELLS; RATS
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; BODY; BRAIN; CENTRAL NERVOUS SYSTEM; CEREBRUM; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; MAMMALS; NERVOUS SYSTEM; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; SOMATIC CELLS; SYNTHESIS; VERTEBRATES