Published 1987
| Version v1
Book
Examination of human brain tumors in situ with image-localized H-1 MR spectroscopy
Description
Human brain tumors were examined in situ by combined imaging and H-1 MR spectroscopy at 1.5 T. Water-suppressed localized H-1 MR spectra obtained from the brains of normal volunteers show resonances from lactate, N-acetyl aspartate (NAA), creatine, and choline. Several patients suffering from different brain tumors were examined, showing spectral changes in the region of 0.5-1.5 ppm; spectral editing showed that these changes were not due to lactic acid, but to lipid signals. The NAA signal was decreased in the tumors as compared with normal brain. This study shows that H-1 MR spectroscopy can monitor submillimolar changes in chemical composition of human brain tumors in situ
Additional details
Publishing Information
- Publisher
- Radiological Society of North America Inc.
- Imprint Place
- Oak Brook, IL (USA)
- Imprint Title
- Radiological Society of North America 73rd scientific assembly and annual meeting (Abstracts)
- Journal Page Range
- p. 66.
Conference
- Title
- 73. scientific assembly and annual meeting of the Radiological Society of North America.
- Dates
- 29 Nov - 4 Dec 1987.
- Place
- Chicago, IL (USA).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 19075445
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BRAIN; CHEMICAL COMPOSITION; HUMAN POPULATIONS; HYDROGEN; LACTATES; LIPIDS; METABOLISM; NEOPLASMS; NMR SPECTRA; PATIENTS; PHYSIOLOGY; SIGNALS; WATER
- Descriptors DEC
- BODY; CARBOXYLIC ACID SALTS; CENTRAL NERVOUS SYSTEM; DISEASES; ELEMENTS; HYDROGEN COMPOUNDS; NERVOUS SYSTEM; NONMETALS; ORGANIC COMPOUNDS; ORGANS; OXYGEN COMPOUNDS; POLAR SOLVENTS; POPULATIONS; SOLVENTS; SPECTRA