Published September 1992 | Version v1
Journal article Metadata-only

Measurements of T1 and T2 over time in formalin-fixed human whole-brain specimens

Creators

  • 1. Dept. of Diagnostic Radiology, Akademiska Sjukhuset, Uppsala Univ. (Sweden)

Description

T1 and T2 were measured in 5 formalin-fixed human whole-brain specimens as a function of time. Gray matter/white matter contrast reversal was observed around the 4th day and was considered to be due to the greater decrease in T1 in gray than in white matter. A possible explanation for this is that the decomposition of the myelin phospholipid structure by formalin somewhat counteracts the general reductive effect of the fixation procedure on relaxation times. (orig.)

Additional details

Publishing Information

Journal Title
Acta Radiologica
Journal Volume
33
Journal Issue
5
Journal Page Range
p. 400-404.
ISSN
0284-1851
CODEN
ACRAE3

INIS

Country of Publication
Sweden
Country of Input or Organization
Sweden
INIS RN
24015165
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BRAIN; DEATH; DECOMPOSITION; FORMALDEHYDE; IMAGES; IN VITRO; NMR IMAGING; RELAXATION TIME; SPIN-LATTICE RELAXATION; SPIN-SPIN RELAXATION
Descriptors DEC
ALDEHYDES; BODY; CENTRAL NERVOUS SYSTEM; CHEMICAL REACTIONS; DIAGNOSTIC TECHNIQUES; NERVOUS SYSTEM; ORGANIC COMPOUNDS; ORGANS; RELAXATION