Evaluation of uterine cervix cancer hypoxia by PET with 18F-F.E.T.N.I.M.. Relation with squamous cell carcinoma (S.C.C.) and osteopontin tumoral markers

Purpose: to evaluate the imaging feasibility of hypoxia of cervical squamous cell carcinoma by PET with 18F-F.E.T.N.I.M. (Iason). to compare the 18F-F.E.T.N.I.M. uptake to the metabolic uptake in 18F-F.D.G. and to study their relationship with the squamous cell carcinoma, tumoral marker and osteoponin, circulating tracer of hypoxia. Conclusions: the F.E.T.N.I.M. uptake by the tumor is always of lower level than the 18F-F.D.G. uptake. By using the ratio Tumor/Muscle, these preliminary results do not enlighten any correlation between the circulating hypoxia tracer and the tumor uptake of 18F-F.E.T.N.I.M.. (N.C.)