Tif-stimulated deoxyribonucleic acid repair in Escherichia coli K-12
Creators
- 1. Centre National de la Recherche Scientifique, Paris, France
Description
Bacterial survival is significantly increased after ultraviolet irradiation in tif sfi cells, provided that the thermosensitive tif mutation has been expressed at 410C before irradiation. This tif-mediated reactivation of ultraviolet irradiated bacteria needs de novo protein synthesis, as is the case for the tif-mediated reactivation of ultraviolet-irradiated phage lambda. However, in striking contrast to the phage reactivation process, this tif-mediated reactivation is no longer associated with mutagenesis. It also requires the presence of the uvrA+ excision function. These results strongly suggest the existence in Escherichia coli K-12 of a repair pathway acting on bacterial deoxyribonucleic acid which is inducible, error free, and uvr dependent
Additional details
Publishing Information
- Journal Title
- J. Bacteriol.
- Journal Volume
- 143
- Journal Issue
- 2
- Series
- J. Bacteriol.
- Journal Page Range
- 703-709
- ISSN
- 0021-9193
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 12577574
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL PATHWAYS; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL REPAIR; DNA; ESCHERICHIA COLI; GENETIC VARIABILITY; MUTATIONS; RADIOSENSITIVITY; SURVIVAL CURVES; TEMPERATURE DEPENDENCE; ULTRAVIOLET RADIATION
- Descriptors DEC
- BACTERIA; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; BIOLOGICAL VARIABILITY; ELECTROMAGNETIC RADIATION; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; RADIATIONS