Published November 2000 | Version v1
Journal article Metadata-only

Preparation of β-methyl p-iodophenyl pentadecanoic acid (BMIPP) and 125I-BMIPP

Creators

  • 1. Jiangsu Inst. of Nuclear Medicine, Wuxi (China). National Laboratory of Nuclear Medicine

Description

A method with several steps superior to literature has been developed for the preparation of β-methyl p-iodophenyl pentadecanoic acid (BMIPP). The synthesis and physical properties of BMIPP are described. It is characterized by IR, 1HNMR, elemental analysis and MS. 125I-BMIPP can be prepared by three methods: direct labelling, solid-state transfer labelling and Cu(I) assisted labelling. Cu(I) assisted labelling is simple and not necessary to purity before clinical use. It fulfil the requirements for kit labelling

Additional details

Publishing Information

Journal Title
Nuclear Science and Techniques
Journal Volume
11
Journal Issue
4
Journal Page Range
p. 240-246
ISSN
1001-8042

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
33015584
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
AROMATICS; CHEMICAL ANALYSIS; CHEMICAL PREPARATION; HYDROGEN 1; INFRARED SPECTRA; IODINE 125; LABELLING; MASS SPECTROSCOPY; MONOCARBOXYLIC ACIDS; NMR SPECTRA; ORGANIC IODINE COMPOUNDS
Descriptors DEC
BETA DECAY RADIOISOTOPES; CARBOXYLIC ACIDS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; HYDROGEN ISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IODINE ISOTOPES; ISOTOPES; LIGHT NUCLEI; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; RADIOISOTOPES; SPECTRA; SPECTROSCOPY; STABLE ISOTOPES; SYNTHESIS