Production and quality control of Indium-111 pentetreotide (OctreoScan) radiopharmaceutical in Iran

¹¹¹In pentetreotide radiopharmaceutical is used extensively for detection of variety of cancers in medicine. Octerotide is a pharmaceutical with a structure similar to somatostatin which administrated via intravenous injection in an ¹¹¹In-labeled form. This radiopharmaceutical acts as a theranostic agent with binding to somatostatin receptors. Over the last decade, ¹¹¹In pentetreotide has remained the most widely used radiopharmaceutical for the scintigraphic detection and staging of primary and metastatic neuroendocrine tumors. The whole process of production of ¹¹¹In radionuclide as well as Indium-111 pentetreotide was tested and the result confirmed the ability of production of this radiopharmaceutical in upcoming years in Iran