Encapsulation of bioactives on magnetite nanoparticles: a targeted drug delivery approach

Plant bioactives having antioxidant and medicinal properties are being targeted for treatment of cancer and various diseases and their market is increasing rapidly in a highly polluting environment. Most of the plant bioactives are hydrophobic in nature, having high rate of metabolism and rapid systemic clearance, thus resulting in their poor bioavailability and lower therapeutic efficacy. Nanoparticles when conjugated with plant bioactives exhibit increased bioavailability and enhanced pharmacological activity. Magnetite nanoparticles represent unique class of drug delivery vehicles due to their magnetic behaviour and thus have potential use in biomedicine