Published January 1991 | Version v1
Journal article Metadata-only

The influence of a tumor-necrotic factor on repair of haemopoietic colony-forming cells of the irradiated mice

Creators

  • 1. Akademiya Meditsinskikh Nauk SSSR, Obninsk (USSR). Nauchno-Issledovatel'skij Inst. Meditsinskoj Radiologii

Description

The influence of a tumor-necrotic factor (TNF) on the CFUs population has been studied normally and after irradiation. An inhibitory effect on the pool of the seven-day and doubling of the yield of the eleven-day colonies have been observed in mice received TNF 20 h before bone narrow removal as compared with the controls. The kinetics of restoration of bone marrow cellularity and CFUs number in mouse-donors treated with TNF 20 h before irradiation (5.0 Gy) has demonstrated the stimulator effect of the agent on both indices

Additional details

Additional titles

Original title (Russian)
Действие туморнекротического фактора (TNF) на процессы восстановления гемопоэтических колониеобразующих клеток у облученных мышей

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
31
Journal Issue
1
Series
Radiobiologiya.
Journal Page Range
92-96
ISSN
0033-8192
CODEN
RADOA

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
23016800
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RECOVERY; BONE MARROW; CFU; EARLY RADIATION EFFECTS; GAMMA RADIATION; INTERFERON; LYMPHOKINES; MICE; RADIATION SYNDROME; RESPONSE MODIFYING FACTORS; SPLEEN
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; ELECTROMAGNETIC RADIATION; HEMATOPOIETIC SYSTEM; IONIZING RADIATIONS; MAMMALS; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; TISSUES; VERTEBRATES