Radiographic evidence of the action of biphosphonate on immature skeleton

We present one patient with Juvenile Idiopathic Osteoporosis (JIO) who was treated with Zolendronic Acid, and a small series Osteogenesis Imperfect (OI) patients administered on eyelie Pamidronate proteol. We describe dense lines in radiographs of tubular bones and pelvis of these patients appearing. After biphosphonates treatment, those images are similar to Harris Lines (Growth Arrest Lines) that appear occasionally by several causes on immature skeletons land through life.