Published August 1975 | Version v1
Journal article Metadata-only

Behaviour of intestinal lactase after irradiation

Creators

  • 1. Florence Univ. (Italy). Istituto di Radiologia

Description

The behaviour of intestinal lactase has been studied in rats after irradiation. The significant increase of activity is not immediate, but slowly and progressively starting from 4 hrs after irradiation. The modifications of the activity are slow and gradual also during the reduction phase. This disaccharase does not show a return to normal values even after three weeks. We suggest the hypothesis that the increase could be due to a modification of the normal synthesis of enzymes caused by irradiation. (orig.)

Abstract (German)

Das Verhalten der Darmlaktase bei bestrahlten Ratten wurde untersucht. Die signifikante Steigerung der Aktivitaet setzt nicht sofort ein, sondern entwickelt sich ab der vierten Stunde nach der Bestrahlung langsam und progressiv. Auch waehrend der Reduktionsphase gehen die Veraenderungen der Aktivitaet langsam und allmaehlich vor sich. Diese Disaccharase zeigt auch nach drei Wochen noch keine Rueckkehr zu normalen Werten. Wir vermuten, dass diese Steigerung auf eine strahlenbedingte Veraenderung der normalen Enzymsynthese zurueckzufuehren ist. (orig./AK)

Additional details

Publishing Information

Journal Title
Strahlentherapie
Journal Volume
150
Journal Issue
2
Series
Strahlentherapie.
Journal Page Range
145-148

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
7257444
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
CELL CYCLE; FRACTIONATED IRRADIATION; GAMMA RADIATION; INHIBITION; INTESTINES; METABOLISM; OXIDOREDUCTASES; PEPTIDE HYDROLASES; RADIATION DOSE UNITS; RADIATION EFFECTS; RADIATION SYNDROME; RADIOBIOLOGY; RATS; SYNTHESIS; TIME DEPENDENCE
Descriptors DEC
ANIMALS; BIOLOGY; BODY; DIGESTIVE SYSTEM; ELECTROMAGNETIC RADIATION; ENZYMES; GASTROINTESTINAL TRACT; HYDROLASES; IONIZING RADIATIONS; IRRADIATION; MAMMALS; ORGANS; RADIATIONS; RODENTS; UNITS; VERTEBRATES

Optional Information

Notes
1 fig.; 13 refs.