Published August 1996 | Version v1
Journal article Metadata-only

Elemental quantitative analysis at the cellular level by synchrotron radiation X-ray fluorescences

Creators

  • 1. Beijing Medical University, Beijing (China)

Description

The changes on composition, concentration of some essential trace elements in cells under various physiological and pathological status were investigated. Synchrotron radiation X-ray fluorescences (SR-XRF) were applied to analyse the change of cellular Fe, Zn contents and their interrelation in aged and anoxic cells, as well as injured cells by free radicals. In all three groups malondialdehyde (MDA) content was raised together with the Fe/Zn ratio. Zinc or metallothionein (MT), could inhibit lipoperoxidation by decreasing MDA and Fe/Zn ratio. Iron, zinc and their ratio vary in accordance with the physiological status of the cell. SR-XRF is a powerful tool for the quantitative analysis of trace elements in samples of cells

Additional details

Publishing Information

Journal Title
Chinese Journal of Nuclear Medicine
Journal Volume
16
Journal Issue
3
Journal Page Range
p. 149-151.
ISSN
0253-9780
CODEN
CITCDE

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
28006939
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
ANIMALS; BRAIN; ELEMENTS; IRON; LIVER; QUANTITATIVE CHEMICAL ANALYSIS; SYNCHROTRON RADIATION; TRACE AMOUNTS; X-RAY FLUORESCENCE ANALYSIS; ZINC
Descriptors DEC
BODY; BREMSSTRAHLUNG; CENTRAL NERVOUS SYSTEM; CHEMICAL ANALYSIS; DIGESTIVE SYSTEM; ELECTROMAGNETIC RADIATION; GLANDS; METALS; NERVOUS SYSTEM; NONDESTRUCTIVE ANALYSIS; ORGANS; RADIATIONS; TRANSITION ELEMENTS; X-RAY EMISSION ANALYSIS