Published February 2008
| Version v1
Journal article
The variation of D-loop in mitochondrial genome and the mutation induced by irradiation
Creators
- 1. National Inst. for Radiation Protection, Chinese Center for Disease Control and Prevention, Beijing (China)
Description
As the non-code region of mitochondrial genome, the displacement-loop region (D-loop) controls the replication and transcription of mtDNA, but it is easy to be altered. The variation, including mutation and polymorphism, plays an important role in disease. Finally, the status quo of radiation induced D-loop variation and its perspective were outlined. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radiation Research and Radiation Processing
- Journal Volume
- 26
- Journal Issue
- 1
- Journal Page Range
- p. 1-4
- ISSN
- 1000-3436
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 41050004
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- DISEASES; DNA; DNA REPLICATION; GENE MUTATIONS; GENES; GENETIC VARIABILITY; IRRADIATION; MITOCHONDRIA; RADIATION INDUCED MUTANTS; RFLPS; TRANSCRIPTION
- Descriptors DEC
- BIOLOGICAL VARIABILITY; CELL CONSTITUENTS; MUTANTS; MUTATIONS; NUCLEIC ACID REPLICATION; NUCLEIC ACIDS; ORGANIC COMPOUNDS
Optional Information
- Notes
- 22 refs.