Published 1991
| Version v1
Book
Induction of micronuclei and binucleated cells by treatment with radiation and cisplatin in CHO cells
- 1. Nuclear Energy Board, Dublin (Ireland)
- 2. Valencia Univ. (Spain). Facultad de Ciencias Biologicas
Description
The frequencies of CHO cells with micronuclei in the cisplatin-treated cultures showed an increase reaching a maximum 48 hours after treatment. Within the next 48 hours a slight decrease in the frequencies was observed. In γ-irradiated cultures (1.2 Gy/min at 80 cm source-skin distance) the maximum in micronuclei-induction was reached at 24 hours post-irradiation, decreasing thereafter. Cultures receiving both treatments showed a similar curve, with a peak at 24 hours, decreasing thereafter. (UK)
Additional details
Publishing Information
- Publisher
- Taylor and Francis.
- Imprint Place
- London (United Kingdom)
- ISBN
- 0-7484-0020-6
- Imprint Title
- New developments in fundamental and applied radiobiology
- Imprint Pagination
- 460 p.
- Journal Page Range
- p. 150-157.
Conference
- Title
- 23. annual meeting of the European Society for Radiation Biology.
- Dates
- 23-26 Sep 1990.
- Place
- Dublin (Ireland).
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 23019013
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- CHO CELLS; DOSE RATES; GAMMA RADIATION; MUTAGENESIS; PLATINUM COMPLEXES; RADIOSENSITIVITY; RESPONSE MODIFYING FACTORS
- Descriptors DEC
- ANIMAL CELLS; COMPLEXES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; RADIATIONS; SOMATIC CELLS; TRANSITION ELEMENT COMPLEXES