Published September 1975
| Version v1
Journal article
Silver oxide oxidation of an aldehyde with carbon tritium bonds vicinal to the carbonyl carbon
Description
The NH4OH-dependent silver oxide oxidation of D,L-[3-3H2) malate semialdehyde-4-al to D,L-[3-3H2] malate was studied. A method is presented allowing carboxylate formation immediately subsequent to aldehyde generation by periodate cleavage. It was found that at high concentrations of Ag2O, base-catalyzed detritiation of the semialdehyde is minimal, ranging 0.5 infinity. The yield of malate appears to be quantitative. Thus, this method allows oxidation of an aldehyde to its carboxylate in high yield while preserving the configuration of the adjacent carbon atom
Additional details
Identifiers
Publishing Information
- Journal Title
- Analytical Biochemistry
- Journal Volume
- 68
- Journal Issue
- 1
- Series
- Anal. Biochem.
- Journal Page Range
- 316-320
- ISSN
- 0003-2697
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 7236132
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Descriptors DEI
- ALDEHYDES; AMMONIUM HYDROXIDES; ISOTOPE EFFECTS; OXIDATION; SILVER OXIDES; TRITIUM; TRITIUM COMPOUNDS
- Descriptors DEC
- AMMONIUM COMPOUNDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CHALCOGENIDES; CHEMICAL REACTIONS; HYDROGEN COMPOUNDS; HYDROGEN ISOTOPES; HYDROXIDES; ISOTOPES; LIGHT NUCLEI; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; OXIDES; OXYGEN COMPOUNDS; RADIOISOTOPES; SILVER COMPOUNDS; TRANSITION ELEMENT COMPOUNDS; YEARS LIVING RADIOISOTOPES
Optional Information
- Notes
- Updated automatically by Metadata and Full-Text Enrichment Agent