Published 1981
| Version v1
Miscellaneous
Suppressor T cells in the graft versus host disease in mice
Creators
- 1. Gezondheidsorganisatie TNO, Rijswijk (Netherlands). Radiobiologisch Inst. TNO
Description
Suppressor T cells are a subpopulation of T lymphocytes, described in the literature as cells interfering with T or B cell-mediated immune reactions. It is also evident that suppressor T lymphocytes are involved in transplantation tolerance. The authors attempted to demonstrate a suppressing activity of lymphoid cells in the acute Graft versus Host Disease (GvHD). The GvHD animal model used in this study consisted of (CBA/Rij x C57BL/Rij)F1 recipients total body irradiated (TBI) with a dose of 8.8 Gay and grafted with 106 CBA/Rij bone marrow cells and 106 CBA/Rij spleen cells (GvHD graft). (Auth.)
Additional details
Publishing Information
- Imprint Title
- REP annual report 1979
- Imprint Pagination
- 488 p.
- Journal Page Range
- p. 351-353.
- Report number
- INIS-mf--6241
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 12575360
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Progress Report
- Descriptors DEI
- BONE MARROW CELLS; GRAFT-HOST REACTION; GRAFTS; IMMUNOSUPPRESSION; LYMPHOCYTES; MICE; MORTALITY; RADIATION CHIMERAS; SPLEEN CELLS; THYMUS CELLS; WHOLE-BODY IRRADIATION
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CHIMERAS; CONNECTIVE TISSUE CELLS; EXTERNAL IRRADIATION; IRRADIATION; LEUKOCYTES; MAMMALS; MOSAICISM; RODENTS; SOMATIC CELLS; TRANSPLANTS; VERTEBRATES