Clinical and immunohistopathological study of primary malignant lymphoma of the brain

Eight cases of primary malignant lymphoma of the brain were examined clinically and immunohistopathologically. According to the LSG classification the patients were subclassified into 5 with diffuse large cell type, 2 with diffuse medium-sized cell type and one with diffuse mixed cell type. Immunohistological stainings demonstrated that all of them were of B lymphocyte origin. Two cases had multiple lesions which were seen in the periventricular area. Tumor response for the treatment consisted of surgery followed by radiation therapy was exellent except for one. Only 2 patients were alive and well at 24 months and 27 months. (author)