biochemical studies o the effect of gonadotropin hormones on the growth of six organs of rats

a major share of the control of sexual functions in both the male and female begins with secretion of gonadotropin releasing hormone (GnRH) by the hypothalamus. this hormone simulates the anterior pituitary gland to secrete two other hormones called gonadotropin hormones, luteinizing hormone (LH) and follicle stimulating hormone (FSH). in this present study five groups of young rats (two weeks old ) were arranged, each group consisted of 8 rats and subdivided into two subgroups, subgroup one consisted of four male and subgroup two consisted of four female rats. the first group was the non-injected control group , while the other groups were injected intravenous with variable doses of FSH and LH at time intervals of one week for five weeks. After injection of FSH and LH hormones, blood samples were obtained from each rat and FSH and LH hormones were measured using immunoradiometric assay technique.at the end of the injection schedule of FSH and LH the male sex assay technique.At the end of the injection schedule of FSH and LH the male sex organs (testes) and the female organs (ovaries) were dissected, isolated and weighted for each rat . Comparing the sex organs of the injected groups with that of non - injected group , significant variations in weight , morphology and size were observed according to the dose of FSH and LH injected. From this study the effect of gonadotropin hormones therapy on the growth of sex organs was observed