Published August 1986
| Version v1
Journal article
Rhodium(III) as a potentiator of the effects of X-rays on cells
- 1. Dartmouth-Hitchcock Medical Center, Hanover, NH (USA). Norris Cotton Cancer Center
- 2. Texas Univ., Austin (USA). Lab. of Radiation Biology
Description
A rhodium compound, Rh(NH3)3Cl3, does not sensitize the spores of Bacillus megaterium to X-rays. However, it is a very effective sensitizer of vegetative cells of Staphylococcus aureus, raising the sensitivity four times in O2 and over 100 times in anoxia. The inhibition by oxygen of the sensitizing action of Rh(III), which operates over a wide range of [O2], is noteworthy. These experiments were performed in saline-phosphate buffer using 50 kVp X-rays. The results are discussed in terms of the known radiation chemistry of this compound. (author)
Additional details
Publishing Information
- Journal Title
- Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.
- Journal Volume
- 50
- Journal Issue
- 2
- Series
- Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.
- Journal Page Range
- 337-343
- ISSN
- 0020-7616
- CODEN
- IJRBA
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 18001802
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- AMMONIUM COMPLEXES; ANOXIA; BACILLUS MEGATERIUM; BACTERIAL SPORES; RADIOSENSITIZERS; RESPONSE MODIFYING FACTORS; RHODIUM CHLORIDES; STAPHYLOCOCCUS; X RADIATION
- Descriptors DEC
- BACILLUS; BACTERIA; CHLORIDES; CHLORINE COMPOUNDS; COMPLEXES; DRUGS; ELECTROMAGNETIC RADIATION; HALIDES; HALOGEN COMPOUNDS; IONIZING RADIATIONS; MICROORGANISMS; RADIATIONS; RHODIUM COMPOUNDS; SPORES; TRANSITION ELEMENT COMPOUNDS