Published May 1993
| Version v1
Journal article
Brain perfusion SPECT in children with frequent fits
- 1. Helsinki Univ. Central Hospital (Finland). Meilahti Clinic
Description
We studied 14 children with frequent fits using 99mTc-HM-PAO single photon emission computed tomography (SPECT). There were 11 patients with partial secondary generalized epilepsy (PSGE) and 3 with Lennox-Gastaut syndrome (LGS). The typical regional cerebral blood flow (rCBF) finding in PSGE was a single area of abnormally low perfused cortex, and that in LGS, multiple hypoperfused areas. Clinically, the LGS patients were more severely affected. SPECT was more sensitive in detecting abnormalities than EEG, CT or MRI. Extensive impairment of rCBF may thus indicate unfavourable development of intellectual performance and poor seizure control. (author)
Additional details
Publishing Information
- Journal Title
- Brain and Development
- Journal Volume
- 15
- Journal Issue
- 3
- Journal Page Range
- p. 214-218.
- ISSN
- 0387-7604
- CODEN
- BRDEER
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 24069664
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD FLOW; CEREBRAL CORTEX; CHILDREN; ELECTROENCEPHALOGRAPHY; EPILEPSY; OXIMES; SINGLE PHOTON ECT; TECHNETIUM 99
- Descriptors DEC
- AMINES; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; BRAIN; CENTRAL NERVOUS SYSTEM; CEREBRUM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; EMISSION COMPUTED TOMOGRAPHY; HOURS LIVING RADIOISOTOPES; HYDROXY COMPOUNDS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MAN; NERVOUS SYSTEM; NERVOUS SYSTEM DISEASES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PRIMATES; RADIOISOTOPES; TECHNETIUM ISOTOPES; TOMOGRAPHY; VERTEBRATES; YEARS LIVING RADIOISOTOPES