Highly sensitive glucose sensor based on monodisperse palladium nickel/activated carbon nanocomposites

Highlights: • An easy and facile synthesis of highly monodisperse novel PtNi@AC nanocomposites. • The surface of the AC layers appeared effectively and stabilized the metal nanoparticles dimensionally. • Rapid, Sensitive, and Reusable Detection of Glucose by novel nanocomposites. • The excellent electrochemical sensing properties of monodisperse PtNi@AC nanocomposites. • Thanks to the ultrasmall sizes, monodispersity and high Pt and Ni % surface of novel materials. - Abstract: Glucose enzyme biosensors have been used for a variety of applications such as medical diagnosis, bioprocess engineering, beverage industry and environmental scanning etc. and there is still a growing interest in glucose sensors. For this purpose, addressed herein, as a novel glucose sensor, highly sensitive activated carbon (AC) decorated monodisperse nickel and palladium alloy nanocomposites modified glassy carbon electrode (Ni-Pd@AC/GCE NCs) have been synthesized by in-situ reduction technique. Raman Spectroscopy (RS), X-ray Photoelectron Spectroscopy (XPS), X-ray Diffraction (XRD), Transmission Electron Microscopy (TEM), cyclic voltammetry (CV) and chronoamperometry (CA) were used for the characterization of the prepared non-enzymatic glucose sensor. The characteristic sensor properties of the Ni-Pd@AC/GCE electrode were compared with Ni-Pd NCs/GCE, Ni@AC/GCE and Pd@AC/GCE and the results demonstrate that the AC is very effective in the enhancement of the electrocatalytic properties of sensor. In addition, the Ni-Pd@AC/GCE nanocomposites showed a very low detection limit of 0.014 μM, a wide linear range of 0.01 mM–1 mM and a very high sensitivity of 90 mA mM⁻¹ cm⁻². Furthermore, the recommended sensor offer the various advantageous such as facile preparation, fast response time, high selectivity and sensitivity. Lastly, monodisperse Ni-Pd@AC/GCE was utilized to detect glucose in real sample species.