Ureter and bladder urinary oxygen pressure relation with graft function and acute tubular necrosis after living non related renal transplantation

To asses the value of urinary oxygen pressure for evaluation of renal graft outcome. In this prospective study we evaluated the oxygen pressure of urine samples obtained from urether (Puuo2)and bladder (pbuo2) as a predictor of graft function and outcome in 30 patients whom underwent kidney transplantation. There was statistically significant relationship between puuo2 and pbuo2 and occurrence of acute tubular necrosis (p=0.001). In addition, there was statistically significant relationship between systemic blood pressure and cold ischemic time and occurrence of acute tubular necrosis. Acute tubular necrosis was higher in patients with systolic blood pressure less than 130 mmhg (p= 0.021). This study showed that puuo2 and pbuo2 of recipients is a noninvasive and sensitive test for determination of graft outcome. (author)